Ann Collier, MD
Professor
Department of Medicine, Division of Allergy & Infectious Diseases
Director, UW AIDS Clinical Trials Unit
Associate Director, Center for AIDS Research

Faculty Information

Biography

Dr. Collier's ongoing clinical research interests include antiretroviral therapy, HIV reservoirs and cure, natural and treated history of primary HIV infection, and the effects of antiretroviral therapy on neurological aspects of HIV infection.

Her ongoing studies include collaborative projects to investigate long-acting antiretroviral drugs and regimens, third line antiretroviral treatment in resource-limited settings, observational studies to evaluate factors associated with HIV reservoir size and long-term outcomes in treated HIV infection, determinants of successful screening for participation in AIDS Clinical Trials Group protocols, and a variety of pilot studies of antiviral and anti-inflammatory agents.

Dr. Collier's ongoing collaborations include local projects with Drs. Joanne SteklerJames Mullins, Christina Marra, Sarah Holte, and Robert Coombs as well as collaborations with other U.S.-based and international colleagues.

Sample projects that trainees might become involved with include third line antiretroviral treatment in resource-limited settings, transition of care from research to clinical care settings, barriers for the conduct of clinical trials in resource-limited settings, determinants of HIV reservoir size, and impact of treatment of acute HIV infection on latently infected CD4 T cells. 

Education & Training: 
MD
Geisel School of Medicine at Dartmouth
Hanover, NH
1978
Intern, Mixed Medicine-Pediatrics Program
North Carolina Memorial Hospital
Chapel Hill, NC
1978-1979
Resident
University of Washington
Seattle, WA
1979-1981
Chief Medical Resident, Attending in Medicine
Dartmouth-Hitchcock Medical Center
Hanover, NH/White River Junction, VT
1981-1982
Fellow in Infectious Diseases
University of Washington
Seattle, WA
1982-1985
Post-Doctoral Research Fellow, Tumor Biology
Fred Hutchinson Cancer Research Center
Seattle, WA
1984-1986
Honors: 
Phi Beta Kappa
National Library of Medicine Women Physicians Local Legend
American Medical Women's Association Award
National Library of Medicine Women Physicians Local Legend
Contact
Phone: 
(206) 744-3293
Mailing Address: 

325 9th Ave

Box 359929

Seattle, WA 98104

Publications
Publications: 

Maenza J, Tapia K, Holte S, Stekler JD, Stevens CE, Mullins JI, Collier AC. How often does treatment of primary HIV lead to post-treatment control? Antivir Ther. 2015; 20(8):855-63.
• PubMed Abstract

Stekler JD, McKernan J, Milne R, Tapia KA, Mykhalchenko K, Holte S, Maenza J, Stevens CE, Buskin SE, Mullins JI, Frenkel LM, Collier AC. Lack of resistance to integrase inhibitors among antiretroviral-naïve subjects with primary HIV-1 infection, 2007-2013. Antiviral Therapy 2015; 20(1):77-80.
• PubMed Abstract

Gross R, Zheng L, La Rosa A, Sun X, Rosenkranz SL, Cardoso SW, Ssali F, Camp R, Godfrey C, Cohn SE, Robbins GK, Chisada A, Wallis CL, Reynolds NR, Lu D, Safren SA, Hosey L, Severe P, Collier ACPartner-focused adherence intervention for second-line antiretroviral therapy: A multinational randomized trial (ACTG A5234). Lancet HIV. 2015 Jan 1; 2(1):e12-e19.
• PubMed Abstract

Smith KY, Tierney C, Mollan K, Venuto CS, Budhathoki C, Ma Q, Morse GD, Sax P, Katzenstein D, Godfrey C, Fischl M, Daar ES, Collier AC and the ACTG 5202 Team. Outcomes by sex following treatment initiation with atazanavir plus ritonavir or efavirenz with abacavir/lamivudine or tenofovir/emtricitabine. Clin Infect Dis 2014; 58(4):555-63.
• PubMed Abstract

Zheng L, Taiwo B, Gandhi RT, Hunt PW, Collier AC, Flexner C, Bosch RJ. Factors associated with CD8+ T-cell activation in HIV-1-infected patients on long-term antiretroviral therapy. JAIDS. 2014 Oct 1; 67(2):153-60.
• PubMed Abstract

Marra CM, Deutsch R, Collier AC, Morgello S, Letendre S, Clifford D, Gelman B, McArthur J, McCutchan JA, Simpson DM, Duarte NA, Heaton RK and Grant. Neurocognitive impairment in HIV-infected individuals with previous syphilis. Intern J STDs AIDS. 2013 May; 24(5):351-5.
• PubMed Abstract