Christine M. Johnston, MD, MPH
Associate Professor
Department of Medicine, Division of Allergy and Infectious Diseases
Associate Director, Infectious Diseases Fellowship Training Program
Associate Medical Director, UW Virology Research Clinic
Research Affiliate, Fred Hutchinson Cancer Research Center

Faculty Information

Biography

Dr. Johnston is a physician-scientist who performs clinical studies of genital herpes simplex virus type 2 (HSV-2) infection, focused on characterizing spatial localization of subclinical genital shedding and host-virus interactions. In addition, research interests include studies of existing and novel antiviral agents to suppress HSV-2 genital shedding, and the interactions between HSV-2 and coinfections in the female genital tract, specifically HIV-1 and bacterial vaginosis.

Education & Training: 
MD
University of Minnesota Medical School
Minneapolis MN
2001
MPH
School of Public Health and Community Medicine, University of Washington
Seattle WA
2007
Residency
Department of Medicine, University of Washington
Seattle WA
2001-2004
Fellowship in Infectious Diseases
Department of Medicine, University of Washington
Seattle WA
2004-2007
Honors: 
Alfred D Milburn Scholarship, University of Minnesota
1998
Neal and Sarah Gault International Study Award, University of Minnesota
2001
Joel E Meyers Infectious Disease Scholarship Award, Fred Hutchinson Cancer Research Center
2004
Contact
Phone: 
(206) 520-4340
Mailing Address: 

325 9th Ave

Box 359928

Seattle, WA 98104

Publications
Publications: 

Johnston C, Zhu J, Jing L, Laing KJ, McClurkan C, Klock A, Diem K, Jin L, Stanaway J, Tronstein E, Kwok W, Huang M, Selke S, Fong Y, Magaret A, Koelle DM, Wald A, Corey L. Virologic and immunologic evidence of multifocal genital herpes simplex virus type 2 infection. J Virol. 2014; 88(9):4921-31.
• Journal of Virology Abstract

Johnston C, Koelle DM, Wald A. Current status and prospect for development of an HSV vaccine. Vaccine. 2014; 32(14):1553-60.
• PubMed Abstract

Johnston C, Saracino M, Kuntz S, et al. Standard-dose and high-dose daily antiviral therapy for short episodes of genital HSV-2 reactivation: three randomised, open-label, cross-over trials. Lancet. 2012; 179(9816):641-7.
• PubMed Abstract

Johnston C, Koelle DM, Wald A. HSV-2: in pursuit of a vaccine. J Clin Invest. 2011; 121(12),4600-9.
• PubMed Abstract

Tronstein E, Johnston C, Huang M, et al. Genital shedding of herpes simplex virus among symptomatic and asymptomatic persons with HSV-2 infection. JAMA. 2011; 305(14):1441-9.
• PubMed Abstract

Johnston C, Orem J, Okuku F, Kalinaki M, Saracino M, Mbidde-Katongole E. Impact of HIV infection and Kaposi Sarcoma on human herpesvirus-8 mucosal and replication and dissemination in Uganda. PLoS ONE. 2009; 4(1):e4222. 
• PubMed Abstract

Johnston C, Magaret A, Selke S, Remington M, Corey L, Wald A. Herpes simplex virus viremia during primary genital infection. J Infect Dis. 2008; 198(1):31-4. 
• PubMed Abstract