David N. Fredricks, MD
Professor
Department of Medicine, Division of Allergy & Infectious Diseases
Adjunct Professor
Department of Microbiology
Professor
Vaccine & Infectious Disease Division (VIDD) and Clinical Research Division, Fred Hutchinson Cancer Research Center
Director, Microbiome Research Initiative, Fred Hutchinson Cancer Research Center
Member, Vaccines & Infectious Diseases Division (VIDD), Fred Hutchinson Cancer Research Center
Sites of Practice: 
Seattle Cancer Care Alliance
University of Washington Medical Center

Faculty Information

Contact
Phone: 
(206) 667-1935
Mailing Address: 

1100 Fairview Ave North

Box 358080, E4-100

Seattle, WA 98109

Research & Clinical Interests
Research Interests: 

The human microbiome with a focus on the genital tract microbiota and its association with adverse health outcomes, and the gut microbiota of cancer patients as predictor of complications.

Clinical Interests: 
  • Fungal and bacterial infections in patients with cancer
Publications
Publications: 

Srinivasan S, Morgan MT, Fiedler TL, Djukovic D, Hoffman NG, Raftery D, Marrazzo J, Fredricks DN. Metabolic Signatures of Bacterial Vaginosis. MBio. 2015 Apr 14; 6(2). pii:e00204-15.
• PubMed Abstract

Srinivasan S, Morgan MT, Liu C, Matsen FA, Hoffman NG, Fiedler TL, Agnew KJ, Marrazzo JM, Fredricks DN. More than meets the eye: associations of vaginal bacteria with gram stain morphotypes using molecular phylogenetic analysis. PLoS One. 2013 Oct 24; 8(10):e78633.
• PubMed Abstract

Srinivasan S, Hoffman NG, Morgan MT, Matsen FA, Fiedler TL, Hall RW, Ross FJ, McCoy CO, Bumgarner R, Marrazzo JM, Fredricks DN. Bacterial communities in women with bacterial vaginosis: high resolution phylogenetic analysis reveals relationships of microbiota to clinical characteristics. PLoS One. 2012; 7(6):e37818.
• PubMed Abstract

Rickerts V, Khot PD, Myerson D, Ko DL, Lambrecht E, Fredricks DN. Comparison of quantitative real time PCR with sequencing and ribosomal RNA-SISH for the identification of fungi in formalin fixed, paraffin-embedded tissue specimens. BMC Infect Dis. 2011; 11:202.
• PubMed Abstract

Guthrie KA, Yong M, Frieze D, Corey L, Fredricks DN. The impact of a change in antibacterial prophylaxis from ceftazidime to levofloxacin in allogeneic hematopoietic cell transplantation. Bone Marrow Transplant. 2010; 45(4):675-81.
• PubMed Abstract

Fredricks DN, Fiedler T, Marrazzo JM. Molecular identification of bacteria associated with bacterial vaginosis. N Engl J Med. 2005; 353(18):1899-1911.
• PubMed Abstract