M. Juliana McElrath, MD, PhD
Department of Medicine, Division of Allergy & Infectious Diseases
Adjunct Professor
Department of Global Health
Adjunct Professor
Department of Laboratory Medicine & Pathology
Senior Vice President & Director, Vaccine & Infectious Disease Division (VIDD), Fred Hutchinson Cancer Research Center

Faculty Information


Dr. McElrath's laboratory research is focused on the identification and characterization of cellular immune responses that may provide protection against HIV infection or disease. Her studies entail understanding immune responses in persons who demonstrate unique control of infection through cohort studies in Seattle and internationally. A major aspect of her studies is to apply these mechanisms of HIV control to HIV vaccine development. Additional projects include immune correlates research in TB and malaria vaccine development

Specific questions under current investigation include:

What components of T cell immunity elicited early in HIV-1 infection contribute to the control of HIV-1 disease?
Do T cell immune responses play a role in resistance to HIV-1 infection in persons repeatedly exposed by sexual contact?
What is the contribution of antigen-specific mucosal T cells in protecting against HIV-1 exposure?
What elements of immunity correlate with protection against HIV-1 infection by vaccination?
How can innate immunity contribute to improved vaccine design?

These studies are performed in collaboration with Drs. Connie Celum, Lawrence Corey, Steve Self, Tuofu Zhu, James Mullins, Florian Hladik, Nicole Frahm, Jennifer Lund, Martin Prlic, Michael Gale, Thomas Hawn and Steve De Rosa.

Education & Training: 
Medical University of South Carolina
Charleston, SC
PhD, Pathology
Medical University of South Carolina
Charleston, SC
NIH Postdoctoral Traineeship
NIH Merit Award
Burroughs Wellcome Clinical Scientist Award in Translational Research
Puget Sound Business Journal Woman of Influence