Paul K. Drain, MD, MPH, FACP
Associate Professor
Department of Medicine, Division of Allergy & Infectious Diseases
Associate Professor
Department of Global Health, Medicine, Epidemiology
Associate Director, Tuberculosis Research and Training Center
Sites of Practice: 
Harborview Medical Center
University of Washington Medical Center

Faculty Information

Biography

Dr. Drain's clinical research focuses on evaluating rapid diagnostic tests and strategies, including novel point-of-care technologies, for infectious diseases in resource-limited settings. The long-term goal of his research is to improve the diagnosis and treatment for tuberculosis, HIV, and HIV-related opportunistic infections. To achieve these goals, Dr. Drain has been conducting clinical research in eastern Africa since 2003 and in South Africa since 2010, where he has developed strong collaborations with the University of KwaZulu-Natal, the Centre for the AIDS Programme of Research in South Africa (CAPRISA), the KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH), and several clinical sites throughout South Africa's KwaZulu-Natal province and Chiang Mai, Thailand. Dr. Drain also collaborates with bioengineering laboratories at the University of Washington, Harvard Medical School, and the University of California on the development and validation new rapid, clinic-based tests for infectious diseases in resource-limited settings.

 

 

Education & Training: 
MPH
University of Washington, School of Public Health
Seattle WA
2001
MD
University of Washington, School of Medicine
2007
Resident
Stanford University
Palo Alto, CA
2008-2010
Clinical and Research Fellow
Massachusetts General Hospital and Brigham, Harvard Medical School
Boston, MA
2011-2013
Honors: 
Trainee Support Grant, Center for AIDS Research, University of Washington, Seattle, WA
2002
Puget Sound Partners for Global Health Award, Seattle, WA
2003
David E. Rogers Fellowship, New York Academy of Medicine, New York, NY
2003
International Health Opportunities Program Grant, University of Washington, Seattle, WA
2003
Student Subspecialty Research Award, Western Student Medical Research Forum, Carmel, CA
2003
Trainee Support Grant, Center for AIDS Research, University of Washington, Seattle, WA
2004
Ellison Medical Foundation Fellowship in Global Health, Fogarty International Center, NIH
2005
Associate Award, Northern California Chapter of the American College of Physicians
2008
Fellowship, MEDICC (Medical Education Cooperation with Cuba)
2008
Scholarship, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA
2008
Velji Emerging Leader in Global Health Award, Global Health Education Consortium
2009
Travel Grant, Dean’s Office, Stanford University School of Medicine, Palo Alto, CA
2009
Schwartz Scholarship, Harvard Medical School, Boston, MA
2010
International Travel Fellowship in Support of Global ID Research, Harvard University, MA
2011
Fogarty International Clinical Research Fellows Program, Fogarty International Center, NIH
2011
Faculty Teaching Award, Harvard Medical School, Boston, MA
2011
David Brudnoy Scholar Award, Massachusetts General Hospital, Boston, MA
2012
International Travel Fellowship in Support of Global ID Research, Harvard University, MA
2012
Harvard HIV Research Training Grant, National Institute of Allergy and Infectious Diseases, NIH
2012
HIV Medicine Association (HIVMA) Travel Award
2012
Fogarty Alumni Travel Award, Fogarty International Center, NIH
2013
Postdoctoral Fellowship Award for Clinical Research, Fund for Medical Discovery, Massachusetts General Hospital Executive Committee on Research, Boston, MA
2013
Merle A. Sande Fellowship in International Infectious Diseases, Infectious Disease Society of America (IDSA) and National Foundation for Infectious Diseases
2013
Global Travel Grant, Center of Expertise in Global & Humanitarian Health, Partners Healthcare
2013
Scholar Award, Harvard University Center for AIDS Research, Harvard University, Boston, MA
2013
Young Investigator Award, Conference on Retroviruses and Opportunistic Infections (CROI
2013
Fellowship, American College of Physicians, Philadelphia, PA
2015
New Investigator Award, University of Washington Center for AIDS Research (CFA
2016
Contact
Phone: 
(206) 520-3820
Mailing Address: 
HMC# 359927
 
325 9th Ave
 
Seattle WA 98104-2499
Research & Clinical Interests
Research Interests: 
  • Tuberculosis
  • HIV
  • SARS-CoV2-2
  • point-of-care diagnostics
  • implementation science
  • clinical epidemiology
  • bioengineering
  • health equality
  • population health
Clinical Interests: 
  • HIV/AIDS
  • Tuberculosis
  • SARS-CoV2-2
  • STIs
  • other global infections of importance
Publications
Publications: 

Drain PK, Kleene JM, Coleman SM, Losina E, Katz JN, Giddy J, Ross D, Freedberg KA, Bassett IV. Prevalence of Cryptococcal Antigenuria at Initial HIV Diagnosis in KwaZulu-Natal. HIV Medicine. 2015 Nov; 16(10):640-4.
• PubMed Abstract

Liu E, Makubi A, Drain P, Spiegelman D, Sando D, Li N, Chalamilla G, Sudfeld CR, Hertzmark, Fawzi WW. Tuberculosis incidence rate and risk factors among HIV-infected adults with access to antiretroviral therapy in Tanzania. AIDS. 2015 Jul 17; 29(11):1391-9.
• PubMed Abstract

Drain PK, Losina E, Coleman SM, Giddy J, Ross D, Katz JN, Bassett IV. Value of Urine Lipoarabinomannan Grade and Second Test for Optimizing Clinic-based Screening for HIV-associated Pulmonary Tuberculosis. J Acquir Immun Defic Syndr. 2015 Mar 1;68(3):274-80.
• PubMed Abstract

Drain PK, Gounder L, Grobler A, Sahid F, Bassett IV, Moosa MYS. Urine Lipoarabinomannan to Monitor anti-Tuberculosis Therapy Response and Predict Mortality in an HIV-endemic Region:  A Prospective Cohort Study. BMJ Open. 2015 Apr 15; 5(4):e006833.
• BMJ Abstract

Cohen GM, Drain PK, Noubary F, Cloete C, Bassett IV. Diagnostic delays and clinical decision making with centralized Xpert MTB/RIF testing in Durban, South Africa. J Acquir Immun Defic Syndr. 2014; 67:e88-93.
• PubMed Abstract

Drain PK, Losina E, Coleman SM, Giddy J, Ross D, Katz JN, Walensky RP, Freedberg KA, Bassett IV. Diagnostic Accuracy of a Point-of-Care Urine Test for Tuberculosis Screening Among Newly-Diagnosed HIV-infected Adults:  A Prospective, Clinic-Based Study. BMC Infectious Diseases. 2014; 14:110.
• PubMed Abstract

Drain PK, Hyle EP, Noubary F, Freedberg KA, Wilson D, Bishai WR, Rodriguez W, Bassett IV. Diagnostic point-of-care tests in resource-limited settings. Lancet Infect Dis. 2014; 14:239-49.
• The Lancet Abstract

Drain PK, Mayeza L, Bartman P, Hurtado R, Moodley P, Varghese S, Maartens G, Alvarez GG, Wilson D. Diagnostic accuracy and clinical role of rapid C-reactive protein testing in HIV-infected individuals with presumed tuberculosis in South Africa. Int J Tuber Lung Dis. 2014; 18:20-27.
• PubMed Abstract

Behforouz HL, Drain PK, Rhatigan JJ. *All authors contributed equally. Rethinking the Social History. New Engl J Med, 2014 Oct 2; 371(14):1277-9. 
• PubMed Abstract