My primary research interest is improving TB screening and prevention in peripartum women and children in high HIV/TB burden settings. Recent work has focused on novel non-sputum based TB diagnostics and the effect of pregnancy on LTBI screening and prevention approaches, as well as collaborating with TB immunologist to better understand the unique feature of these populations and how they may effect TB pathogenesis.
NIH/NIAID K23 Impact of maternal HIV on Mycobacterium tuberculosis (Mtb) infection among peripartum women and their infants (PI: LaCourse) Mentors: Grace John-Stewart (UW), Amita Gupta (Johns Hopkins)
Thrasher Foundation Preventing Mycobacterium tuberculosis infection in HIV exposed infants (Co-PI: John-Stewart & Hawn) Role: Project Director, Co-Investigator
NIH/NIAID R01 The effect of HIV exposure and infection on immunity to TB in children (PI: John-Stewart, Day) Role: Co-Investigator
NIH/NIAID R21 NanoDisk-MS measured Mtb antigen peptides for TB diagnosis and treatment monitoring in HIV-infected children (PI: LaCourse) (Co-I Ye Hu, Arizona University BioDesign Institute)
NIH/NICHD R21 Dynamics of tuberculosis immune response in peripartum HIV-infected and HIV-uninfected women (Co-PI: LaCourse, Javeed Shah [UW DAID]) Co-I Jai Lingappa, DGH ICRC)
NIH/UW CFAR New Investigator Award (PI: LaCourse) Oral swab analysis (OSA) for TB diagnosis in women, adolescents, and HIV-infected individuals Mentors: Grace John-Stewart (UW), Gerard Cangelosi (UW Dept of Environmental and Occupational Health)