W. Conrad Liles, MD, PhD
Professor
Department of Medicine, Division of Allergy & Infectious Diseases
Adjunct Professor
Department of Pathology
Adjunct Professor
Department of Pharmacology
Adjunct Professor
Department of Global Health
Associate Chair of Medicine, University of Washington
Co-Director, Molecular Medicine & Mechanisms of Disease (M3D) Graduate Program
Co-Director, Molecular Medicine Training Program
Founding Director, Sepsis Center of Research Excellence-UW (SCORE-UW)
Sites of Practice: 
University of Washington Medical Center

Faculty Information

Biography

Dr. Liles returned to the University of Washington in 2012 from the University of Toronto, where he was Vice-Chair and Professor of Medicine, Director of the Division of Infectious Diseases, and the Canada Research Chair in Infectious Diseases and Inflammation. In addition to his duties as Professor and Associate Chair, Dr. Liles serves as Co-Director of the Molecular Medicine Training Program at the University of Washington. 

Education & Training: 
MD
University of Washington
Seattle, WA
1987
PhD
University of Washington, Department of Pharmacology
Seattle, WA
1987
Residency
Massachusetts General Hospital
Boston, MA
1987-1990
Chief Residency
University of Washington Medical Center
Seattle WA
1990-1991
Fellowship, Division of Allergy & Infectious Diseases
University of Washington
Seattle, WA
1991-1994
Honors: 
Fialkow Scholar Award
1998
WSCI Outstanding Investigator Award
2005
Canada Research Chair in Inflammation and Infectious Diseases
2006-2011
Fellow, American College of Physicians (ACP)
1998
Fellow, Infectious Diseases Society of America (IDSA)
2001
Elected member, Association of American Physicians (AAP)
Elected member, American Clinical and Climatological Association (ACCA)
Western Association of Physicians
2012
Association of American Physicians (AAP)
2014
American Clinical and Climatological Association (ACCA)
2016
Contact
Phone: 
(206) 221-6965
Mailing Address: 

1959 NE Pacific St.

Box 356420

Seattle, WA 98195

Research & Clinical Interests
Research Interests: 
  • Sepsis and Critical Illness
  • Tropical Medicine
  • Malaria
  • Congenital Immunonodeficieincy disorders
  • Immuonopathogenesis of life-threatening infections
  • Inflammation
  • Immunomodulatory therapy 
Clinical Interests: 
  • Tropical Medicine
  • Malaria
  • Congenital Immunonodeficieincy disorders
  • Immuonopathogenesis of life-threatening infections
  • Inflammation
  • Immunomodulatory therapy
Publications
Publications: 

Mei, SHJ, Haitsma, JJ, Santos, CC dos, Deng, Y, Lai, PFH, Slutsky, AS, Liles WC, Stewart, DJ. Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis. Am J Respir Crit Care Med. 2010; 182(8):1047-57.
• PubMed Abstract

Ricciuto, DR, Santos, CC dos, Hawkes, M, Toltl, LJ, Conroy, AL, Rajwans, N, Lafferty, EI, Cook, DJ, Fox-Robichaud, A, Kahnamoui, K, Kain, KC, Liaw, PC, Liles WC. Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis. Crit Care Med. 2011; 39(4):702-10.
• PubMed Abstract 

dos Santos C, Murthy S, Hu P, Shan Y, Haitsma JJ, Mei SHJ, Stewart DJ, Liles WC. Network analysis of transcriptional responses induced by mesenchymal stem cell treatment of experimental sepsis. Am J Pathol. 2012; 181(5):1681-92.
 PubMed Abstract 

Lovegrove, FE, Tangpukdee, N, Opoka, RO, Lafferty, EI, Rajwans, N, Hawkes, M, Krudsood, S, Looareesuwan, S, John, CC, Liles WC, Kain, KCl. Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children. PLoS One. 2009; 4(3):e4912

Lovegrove, FE, Gharib, SA, Peña-Castillo, L, Patel, SN, Ruzinski, JT, Hughes, TR, Liles WC, Kain, KC. Parasite burden and CD36-mediated sequestration are determinants of acute lung injury in an experimental malaria model. PLoS Pathog. 2008; 4(5):e1000068. 
 PubMed Abstract