Wesley C. Van Voorhis, MD, PhD
Professor
Department of Medicine, Division of Allergy & Infectious Diseases
Adjunct Professor
Department of Microbiology
Adjunct Professor
Department of Global Health
Director, Center for Emerging and Re-emerging Infectious Diseases (CERID)
Sites of Practice: 
University of Washington Medical Center

Faculty Information

Biography
Education & Training: 
PhD, Immunology
Rockefeller University
New York NY
1976-1983
MD
Cornell University Medical College
New York NY
1978-1984
Resident in Internal Medicine
University of California, San Francisco
San Francisco CA
1985-1986
Fellowship in Infectious Diseases
University of Washington Medical School and Fred Hutchinson Cancer Research Center
Seattle WA
1986-1989
Honors: 
Research Fellowship, Center for Cancer Research, Massachusetts Institute of Technology
1976
National Science Foundation Graduate Student Fellowship
1977
Medical Scientist Training Program Fellowship
1978
Franklyn Ellenbogen Prize in Hematology/Oncology, Cornell University Medical College
1984
Alpha Omega Alpha Honor Society
1986
Award for Excellence, Medical House Officer/Teacher, University of California, San Francisco Medical School, Class of 1986
Searle Scholar Award
1989
PEW Scholar in the Biomedical Sciences Award
Research Career Development Award, NIH
1991
Elected, American Society for Clinical Investigation
1997
Councilor, Western Society for Clinical Investigation
2000-2003
Young Investigator Award, Western Society of Clinical Investigation
2001
Award from 1st Year Medical Student Class for Best Teacher of the Winter 2002 quarter
2002
Award from 1st Year Medical Student Class for Best Teacher of the Winter 2003 quarter
2003
PI of 2003 Project of Year Award from Medicines for Malaria Venture
2003
Secretary Treasurer, Western Society for Clinical Investigation
2003-2006
Elected, American Association of Physicians
2005
Chair (06-08) and Member, Training Program Directors Committee, Infectious Diseases Society of America
2003-2008
Chair, Drug Target Selection Group, Tropical Disease Research Unit, World Health Organization
2005-2012
Science in Medicine Lecturer, University of Washington
2012
President, Western Association of Physicians
2012-2013
Mayo Soley Award for Research Excellence, Western Association of Physicians
2015
Contact
Phone: 
(206) 543-2447
Mailing Address: 

750 Republican St

Box 358061

Seattle, WA 98195-8061

Research & Clinical Interests
Research Interests: 
  • Drug discovery and development for bacterial and parasitic diseases, particularly cryptosporidium, malaria
Clinical Interests: 
  • Travel and tropical medicine
  • General infectious diseases
Publications
Publications: 

Ojo KK, Eastman RT, Vidadala R, Zhang Z, Rivas KL, Choi R, Lutz JD, Reid MC, Fox AMW, Hulverson MA, Kennedy M, Isoherranen N, Kim LM, Comess KM, Kempf DJ, Verlinde CLMJ, Su X-Z, Kappe S, Maly DJ, Fan E, & Van Voorhis WC. Specific inhibitor of PfCDPK4 blocks malaria transmission: Chemical-genetic validation. J Infect Dis. 2014; 209:275-84.
• PubMed Abstract

Baugh L, Gallagher LA, Patrapuvich R, Clifton MC, Gardberg AS, Edwards TE, Armour B, Begley DW, Dieterich SH, Dranow DM, Abendroth J, Fairman JW, Fox D 3rd, Staker BL, Phan I, Gillespie A, Choi R, Nakazawa-Hewitt S, Nguyen MT, Napuli A, Barrett L, Buchko GW, Stacy R, Myler PJ, Stewart LJ, Manoil C, Van Voorhis WC. Combining functional and structural genomics to sample the essential burkholderia structome. PLoS One. 2013; 8(1):e53851.
• PLoS One Abstract

Castellanos-Gonzalez A, A. White AC Jr, Ojo KK, Vidadala R, Zhang Z, Reid MC, Fox AMW, Keyloun KR, Rivas K, Irani A, Dann SM, Fan E, Maly DJ, Van Voorhis WC. A novel Calcium Dependent Protein Kinase Inhibitor as a lead compound for treating Cryptosporidiosis. J Infect. Dis. 2013; 208:1342-8.
• PubMed Abstract

Ojo KK, Pfander C, Mueller NR, Burstroem C, Larson ET, Bryan CM, Fox AM, Reid MC, Johnson SM, Murphy RC, Kennedy M, Mann H, Leibly DJ, Hewitt SN, Verlinde CL, Kappe S, Merritt EA, Maly DJ, Billker O, Van Voorhis WC. Transmission of malaria to mosquitoes blocked by bumped kinase inhibitors. J Clin Invest. 2012; 122(6):2301-5.
• PubMed Abstract

Magarinos MP, Carmona SP, Crowther GJ, Ralph SA, Roos DA, Shanmugam D, Van Voorhis WC, Aguero F. TDR Targets: a chemogenomics resource for neglected diseases. Nucl Acids Res. 2012; 40(Database issue):D1118-27.
• PubMed Abstract

Nwaka S, Besson D, Ramirez B, Maes L, Matheeussen A, Bickle Q, Mansour NR, Yousif F, Townson S, Gokool S, Cho-Ngwa F, Samje M, Misra-Bhattacharya S, Murthy PK, Fakorede F, Paris JM, Yeates C, Ridley R, Van Voorhis WC, Geary T. Integrated Dataset of Screening Hits against Multiple Neglected Disease Pathogens. PLoS Negl Trop Dis. 2011; 5(12):e1412.
• PubMed Abstract

Engelson EJ, Buckner FS, Van Voorhis WC. An essential farnesylated kinesin in Trypanosoma brucei. PLoS One. 2011; 6(11): e26508.
• PubMed Abstract

Guiguemde WA, Shelat AA, Bouck D, Duffy S, Crowther GJ, Davis PH, Smithson DC, Connelly M, Clark J, Zhu F, Jiménez-Díaz MB, Martinez MS, Wilson EB, Tripathi AK, Gut J, Sharlow ER, Bathurst I, El Mazouni F, Fowble JW, Forquer I, McGinley PL, Castro S, Angulo-Barturen I, Ferrer S, Rosenthal PJ, Derisi JL, Sullivan DJ, Lazo JS, Roos DS, Riscoe MK, Phillips MA, Rathod PK, Van Voorhis WC, Avery VM, Guy RK. Chemical genetics of Plasmodium falciparum. Nature. 2010; 465(7296):311-5.
• PubMed Abstract

Ojo KK, Larson ET, Keyloun KR, Castaneda LJ, Derocher AE, Inampudi KK, Kim JE, Arakaki TL, Murphy RC, Zhang L, Napuli AJ, Maly DJ, Verlinde CL, Buckner FS, Parsons M, Hol WG, Merritt EA, Van Voorhis WCToxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors. Nat Struct Mol Biol. 2010; 17:602-7.
• PubMed Abstract