Christine M. Johnston, MD, MPH

Associate Professor

Department of Medicine, Division of Allergy and Infectious Diseases

Associate Director, Infectious Diseases Fellowship Training Program

Associate Medical Director, UW Virology Research Clinic

Research Affiliate, Fred Hutchinson Cancer Research Center

Faculty Information

Biography

Dr. Johnston is a physician-scientist who performs clinical studies of genital herpes simplex virus type 2 (HSV-2) infection, focused on characterizing spatial localization of subclinical genital shedding and host-virus interactions. In addition, research interests include studies of existing and novel antiviral agents to suppress HSV-2 genital shedding, and the interactions between HSV-2 and coinfections in the female genital tract, specifically HIV-1 and bacterial vaginosis.

Education & Training:

University of Minnesota Medical School

Minneapolis MN

2001

MPH

School of Public Health and Community Medicine, University of Washington

Seattle WA

2007

Residency

Department of Medicine, University of Washington

Seattle WA

2001-2004

Fellowship in Infectious Diseases

Department of Medicine, University of Washington

Seattle WA

2004-2007

Honors:

Alfred D Milburn Scholarship, University of Minnesota

1998

Neal and Sarah Gault International Study Award, University of Minnesota

2001

Joel E Meyers Infectious Disease Scholarship Award, Fred Hutchinson Cancer Research Center

2004

Contact

Email:

cjohnsto@uw.edu [5]

Phone:

(206) 520-4340

Mailing Address:

325 9th Ave

Box 359928

Seattle, WA 98104

Publications

PubMed:

PubMed Bibliography [6]

Publications:

Johnston C, Zhu J, Jing L, Laing KJ, McClurkan C, Klock A, Diem K, Jin L, Stanaway J, Tronstein E, Kwok W, Huang M, Selke S, Fong Y, Magaret A, Koelle DM, Wald A, Corey L. Virologic and immunologic evidence of multifocal genital herpes simplex virus type 2 infection. J Virol. 2014; 88(9):4921-31.
• Journal of Virology Abstract [7]

Johnston C, Koelle DM, Wald A. Current status and prospect for development of an HSV vaccine. Vaccine. 2014; 32(14):1553-60.
• PubMed Abstract [8]

Johnston C, Saracino M, Kuntz S, et al. Standard-dose and high-dose daily antiviral therapy for short episodes of genital HSV-2 reactivation: three randomised, open-label, cross-over trials. Lancet. 2012; 179(9816):641-7.
• PubMed Abstract [9]

Johnston C, Koelle DM, Wald A. HSV-2: in pursuit of a vaccine. J Clin Invest. 2011; 121(12),4600-9.
• PubMed Abstract [10]

Tronstein E, Johnston C, Huang M, et al. Genital shedding of herpes simplex virus among symptomatic and asymptomatic persons with HSV-2 infection. JAMA. 2011; 305(14):1441-9.
• PubMed Abstract [11]

Johnston C, Orem J, Okuku F, Kalinaki M, Saracino M, Mbidde-Katongole E. Impact of HIV infection and Kaposi Sarcoma on human herpesvirus-8 mucosal and replication and dissemination in Uganda. PLoS ONE. 2009; 4(1):e4222.
• PubMed Abstract [12]

Johnston C, Magaret A, Selke S, Remington M, Corey L, Wald A. Herpes simplex virus viremia during primary genital infection. J Infect Dis. 2008; 198(1):31-4.
• PubMed Abstract [13]