This is unpublished

Christine M.

Infectious Diseases
Associate Professor Department of Medicine, Division of Allergy and Infectious Diseases
Associate Director, Infectious Diseases Fellowship Training Program
Associate Medical Director, UW Virology Research Clinic
Research Affiliate, Fred Hutchinson Cancer Research Center

Related Links


Dr. Johnston is a physician-scientist who performs clinical studies of genital herpes simplex virus type 2 (HSV-2) infection, focused on characterizing spatial localization of subclinical genital shedding and host-virus interactions. In addition, research interests include studies of existing and novel antiviral agents to suppress HSV-2 genital shedding, and the interactions between HSV-2 and coinfections in the female genital tract, specifically HIV-1 and bacterial vaginosis.

Education & Training

MD, University of Minnesota Medical School, Minneapolis MN (2001)

MPH, School of Public Health and Community Medicine, University of Washington, Seattle WA (2007)

Residency, Department of Medicine, University of Washington, Seattle WA (2001-2004)

Fellowship in Infectious Diseases, Department of Medicine, University of Washington, Seattle WA (2004-2007)


Alfred D Milburn Scholarship, University of Minnesota (1998)

Neal and Sarah Gault International Study Award, University of Minnesota (2001)

Joel E Meyers Infectious Disease Scholarship Award, Fred Hutchinson Cancer Research Center (2004)


Johnston C, Zhu J, Jing L, Laing KJ, McClurkan C, Klock A, Diem K, Jin L, Stanaway J, Tronstein E, Kwok W, Huang M, Selke S, Fong Y, Magaret A, Koelle DM, Wald A, Corey L. Virologic and immunologic evidence of multifocal genital herpes simplex virus type 2 infection. J Virol. 2014; 88(9):4921-31.
• Journal of Virology Abstract

Johnston C, Koelle DM, Wald A. Current status and prospect for development of an HSV vaccine. Vaccine. 2014; 32(14):1553-60.
• PubMed Abstract

Johnston C, Saracino M, Kuntz S, et al. Standard-dose and high-dose daily antiviral therapy for short episodes of genital HSV-2 reactivation: three randomised, open-label, cross-over trials. Lancet. 2012; 179(9816):641-7.
• PubMed Abstract

Johnston C, Koelle DM, Wald A. HSV-2: in pursuit of a vaccine. J Clin Invest. 2011; 121(12),4600-9.
• PubMed Abstract

Tronstein E, Johnston C, Huang M, et al. Genital shedding of herpes simplex virus among symptomatic and asymptomatic persons with HSV-2 infection. JAMA. 2011; 305(14):1441-9.
• PubMed Abstract

Johnston C, Orem J, Okuku F, Kalinaki M, Saracino M, Mbidde-Katongole E. Impact of HIV infection and Kaposi Sarcoma on human herpesvirus-8 mucosal and replication and dissemination in Uganda. PLoS ONE. 2009; 4(1):e4222. 
• PubMed Abstract

Johnston C, Magaret A, Selke S, Remington M, Corey L, Wald A. Herpes simplex virus viremia during primary genital infection. J Infect Dis. 2008; 198(1):31-4. 
• PubMed Abstract