W. Conrad
Liles
MD, PhD
related links
bio
Dr. Liles returned to the University of Washington in 2012 from the University of Toronto, where he was Vice-Chair and Professor of Medicine, Director of the Division of Infectious Diseases, and the Canada Research Chair in Infectious Diseases and Inflammation. In addition to his duties as Professor and Associate Chair, Dr. Liles serves as Co-Director of the Molecular Medicine Training Program at the University of Washington.
research interests
- Sepsis and Critical Illness
- Tropical Medicine
- Malaria
- Congenital Immunonodeficieincy disorders
- Immuonopathogenesis of life-threatening infections
- Inflammation
- Immunomodulatory therapy
clinical interests
- Tropical Medicine
- Malaria
- Congenital Immunonodeficieincy disorders
- Immuonopathogenesis of life-threatening infections
- Inflammation
- Immunomodulatory therapy
education & training
MD, University of Washington, Seattle, WA (1987)
PhD, University of Washington, Department of Pharmacology, Seattle, WA (1987)
Residency, Massachusetts General Hospital, Boston, MA (1987-1990)
Chief Residency, University of Washington Medical Center, Seattle WA (1990-1991)
Fellowship, Division of Allergy & Infectious Diseases, University of Washington, Seattle, WA (1991-1994)
honors
Fialkow Scholar Award (1998)
WSCI Outstanding Investigator Award (2005)
Canada Research Chair in Inflammation and Infectious Diseases (2006-2011)
Fellow, American College of Physicians (ACP) (1998)
Fellow, Infectious Diseases Society of America (IDSA) (2001)
Elected member, Association of American Physicians (AAP)
Elected member, American Clinical and Climatological Association (ACCA)
Western Association of Physicians (2012)
Association of American Physicians (AAP) (2014)
American Clinical and Climatological Association (ACCA) (2016)
publications
Mei, SHJ, Haitsma, JJ, Santos, CC dos, Deng, Y, Lai, PFH, Slutsky, AS, Liles WC, Stewart, DJ. Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis. Am J Respir Crit Care Med. 2010; 182(8):1047-57.
• PubMed Abstract
Ricciuto, DR, Santos, CC dos, Hawkes, M, Toltl, LJ, Conroy, AL, Rajwans, N, Lafferty, EI, Cook, DJ, Fox-Robichaud, A, Kahnamoui, K, Kain, KC, Liaw, PC, Liles WC. Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis. Crit Care Med. 2011; 39(4):702-10.
• PubMed Abstract
dos Santos C, Murthy S, Hu P, Shan Y, Haitsma JJ, Mei SHJ, Stewart DJ, Liles WC. Network analysis of transcriptional responses induced by mesenchymal stem cell treatment of experimental sepsis. Am J Pathol. 2012; 181(5):1681-92.
• PubMed Abstract
Lovegrove, FE, Tangpukdee, N, Opoka, RO, Lafferty, EI, Rajwans, N, Hawkes, M, Krudsood, S, Looareesuwan, S, John, CC, Liles WC, Kain, KCl. Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children. PLoS One. 2009; 4(3):e4912
Lovegrove, FE, Gharib, SA, Peña-Castillo, L, Patel, SN, Ruzinski, JT, Hughes, TR, Liles WC, Kain, KC. Parasite burden and CD36-mediated sequestration are determinants of acute lung injury in an experimental malaria model. PLoS Pathog. 2008; 4(5):e1000068.
• PubMed Abstract