This is unpublished

Wesley C.
Van Voorhis
MD, PhD

Faculty
Infectious Diseases
Pinned
Academic
ProfessorDepartment of Medicine, Division of Allergy & Infectious Diseases
Adjunct Professor Department of Microbiology
Adjunct Professor, Department of Global Health
Professional
Director, Center for Emerging and Re-emerging Infectious Diseases (CERID)
Sites of Practice
University of Washington Medical Center

related links

Research INterests

  • Drug discovery and development for bacterial and parasitic diseases, particularly cryptosporidium, malaria

CLIncal Interests

  • Travel and tropical medicine
  • General infectious diseases

Education & Training:

PhD, Immunology, Rockefeller University, New York NY (1976-1983)

MD, Cornell University Medical College, New York NY (1978-1984)

Resident in Internal Medicine, University of California, San Francisco, San Francisco CA (1985-1986)

Fellowship in Infectious Diseases, University of Washington Medical School and Fred Hutchinson Cancer Research Center, Seattle WA (1986-1989)

Honors:

Research Fellowship, Center for Cancer Research, Massachusetts Institute of Technology (1976)

National Science Foundation Graduate Student Fellowship (1977)

Medical Scientist Training Program Fellowship (1978)

Franklyn Ellenbogen Prize in Hematology/Oncology, Cornell University Medical College (1984)

Alpha Omega Alpha Honor Society (1986)

Award for Excellence, Medical House Officer/Teacher, University of California, San Francisco Medical School, Class of 1986

Searle Scholar Award (1989)

PEW Scholar in the Biomedical Sciences Award

Research Career Development Award, NIH (1991)

Elected, American Society for Clinical Investigation (1997)

Councilor, Western Society for Clinical Investigation (2000-2003)

Young Investigator Award, Western Society of Clinical Investigation (2001)

Award from 1st Year Medical Student Class for Best Teacher of the Winter 2002 quarter (2002)

Award from 1st Year Medical Student Class for Best Teacher of the Winter 2003 quarter (2003)

PI of 2003 Project of Year Award from Medicines for Malaria Venture (2003)

Secretary Treasurer, Western Society for Clinical Investigation (2003-2006)

Elected, American Association of Physicians (2005)

Chair (06-08) and Member, Training Program Directors Committee, Infectious Diseases Society of America (2003-2008)

Chair, Drug Target Selection Group, Tropical Disease Research Unit, World Health Organization (2005-2012)

Science in Medicine Lecturer, University of Washington (2012)

President, Western Association of Physicians (2012-2013)

Mayo Soley Award for Research Excellence, Western Association of Physicians (2015)

Publications

 

Ojo KK, Eastman RT, Vidadala R, Zhang Z, Rivas KL, Choi R, Lutz JD, Reid MC, Fox AMW, Hulverson MA, Kennedy M, Isoherranen N, Kim LM, Comess KM, Kempf DJ, Verlinde CLMJ, Su X-Z, Kappe S, Maly DJ, Fan E, & Van Voorhis WC. Specific inhibitor of PfCDPK4 blocks malaria transmission: Chemical-genetic validation. J Infect Dis. 2014; 209:275-84.
• PubMed Abstract

Baugh L, Gallagher LA, Patrapuvich R, Clifton MC, Gardberg AS, Edwards TE, Armour B, Begley DW, Dieterich SH, Dranow DM, Abendroth J, Fairman JW, Fox D 3rd, Staker BL, Phan I, Gillespie A, Choi R, Nakazawa-Hewitt S, Nguyen MT, Napuli A, Barrett L, Buchko GW, Stacy R, Myler PJ, Stewart LJ, Manoil C, Van Voorhis WC. Combining functional and structural genomics to sample the essential burkholderia structome. PLoS One. 2013; 8(1):e53851.
• PLoS One Abstract

Castellanos-Gonzalez A, A. White AC Jr, Ojo KK, Vidadala R, Zhang Z, Reid MC, Fox AMW, Keyloun KR, Rivas K, Irani A, Dann SM, Fan E, Maly DJ, Van Voorhis WC. A novel Calcium Dependent Protein Kinase Inhibitor as a lead compound for treating Cryptosporidiosis. J Infect. Dis. 2013; 208:1342-8.
• PubMed Abstract

Ojo KK, Pfander C, Mueller NR, Burstroem C, Larson ET, Bryan CM, Fox AM, Reid MC, Johnson SM, Murphy RC, Kennedy M, Mann H, Leibly DJ, Hewitt SN, Verlinde CL, Kappe S, Merritt EA, Maly DJ, Billker O, Van Voorhis WC. Transmission of malaria to mosquitoes blocked by bumped kinase inhibitors. J Clin Invest. 2012; 122(6):2301-5.
• PubMed Abstract

Magarinos MP, Carmona SP, Crowther GJ, Ralph SA, Roos DA, Shanmugam D, Van Voorhis WC, Aguero F. TDR Targets: a chemogenomics resource for neglected diseases. Nucl Acids Res. 2012; 40(Database issue):D1118-27.
• PubMed Abstract

Nwaka S, Besson D, Ramirez B, Maes L, Matheeussen A, Bickle Q, Mansour NR, Yousif F, Townson S, Gokool S, Cho-Ngwa F, Samje M, Misra-Bhattacharya S, Murthy PK, Fakorede F, Paris JM, Yeates C, Ridley R, Van Voorhis WC, Geary T. Integrated Dataset of Screening Hits against Multiple Neglected Disease Pathogens. PLoS Negl Trop Dis. 2011; 5(12):e1412.
• PubMed Abstract

Engelson EJ, Buckner FS, Van Voorhis WC. An essential farnesylated kinesin in Trypanosoma brucei. PLoS One. 2011; 6(11): e26508.
• PubMed Abstract

Guiguemde WA, Shelat AA, Bouck D, Duffy S, Crowther GJ, Davis PH, Smithson DC, Connelly M, Clark J, Zhu F, Jiménez-Díaz MB, Martinez MS, Wilson EB, Tripathi AK, Gut J, Sharlow ER, Bathurst I, El Mazouni F, Fowble JW, Forquer I, McGinley PL, Castro S, Angulo-Barturen I, Ferrer S, Rosenthal PJ, Derisi JL, Sullivan DJ, Lazo JS, Roos DS, Riscoe MK, Phillips MA, Rathod PK, Van Voorhis WC, Avery VM, Guy RK. Chemical genetics of Plasmodium falciparum. Nature. 2010; 465(7296):311-5.
• PubMed Abstract

Ojo KK, Larson ET, Keyloun KR, Castaneda LJ, Derocher AE, Inampudi KK, Kim JE, Arakaki TL, Murphy RC, Zhang L, Napuli AJ, Maly DJ, Verlinde CL, Buckner FS, Parsons M, Hol WG, Merritt EA, Van Voorhis WCToxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors. Nat Struct Mol Biol. 2010; 17:602-7.
• PubMed Abstract